RetinaDigest

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In fovea-off rhegmatogenous retinal detachment, more advanced baseline morphologic stages are associated with significantly worse postoperative visual acuity and metamorphopsia outcomes at all follow-up timepoints through 12 months.

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Rapid resolution of intraretinal and subretinal fluid within 12 weeks of faricimab treatment predicts longer dosing intervals and treatment durability in patients with neovascular age-related macular degeneration.

This multicenter retrospective analysis of 10,247 patients found that initiating faricimab or aflibercept 8 mg achieved better treatment durability (10 vs 9 weeks) and anatomical outcomes compared to switching from older anti-VEGF agents.

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External validation of proposed ROP screening guideline modifications using a large US database showed potential for reducing screening encounters by 2.5-7.8%, but raised safety concerns for Pacific race infants who may require more sensitive screening protocols.

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This case report documents the first detailed description of bilateral panuveitis secondary to B virus infection, demonstrating that prompt antiviral treatment with ganciclovir can prevent blindness in this rapidly progressive zoonotic disease.

This retrospective study of 752 patients with ocular inflammation at an Italian referral center found anterior uveitis (56.34%) was most common, with noninfectious etiologies predominating (77.13%) in a primarily middle-aged, female, Caucasian population.

Socioeconomic disadvantage, measured by Area Deprivation Index (ADI), significantly delays control of ocular inflammation in uveitis patients treated with systemic immunosuppression, with a 10.4% decreased likelihood of control within 12 months for every 10-unit ADI increase.

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This retrospective study of 14 ocular sebaceous neoplasms found that atypical sebaceous neoplasms and 67% of adenomas were mismatch repair (MMR) deficient, suggesting potential association with Muir-Torre syndrome, while sebaceomas showed no MMR deficiency.

A 42-year-old patient on tofacitinib and methotrexate for psoriatic arthritis developed EBV-associated primary vitreoretinal B-cell lymphoma presenting as steroid-refractory vitritis, which resolved following diagnostic pars plana vitrectomy without requiring chemotherapy.

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