RetinaDigest

Weekly curated literature from top retina and ophthalmology journals

18 articles
8 categories
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Retinal Detachment & Trauma2 articles

RRD, TRD, giant tears, PVR, ocular trauma, macular hole, ERM

Clinical Features And Prognosis Analysis Of Rhegmatogenous Retinal Detachment In Patients With Implantable Collamer Lens.

Lin et al.
RetinaJan 7, 2026

Rhegmatogenous retinal detachment in ICL patients can be successfully managed with vitreoretinal surgery without requiring ICL removal, achieving 93% final anatomical success rate with significant visual improvement.

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Resolution of Retained Perfluoro-n-Octane After Retinal Detachment Repair.

Spivey et al.
Ophthalmol RetinaJan 6, 2026

The title indicates a case report or case series documenting the spontaneous resolution of retained perfluoro-n-octane following retinal detachment surgery.

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AMD & Macular Degeneration3 articles

Neovascular AMD, geographic atrophy, submacular hemorrhage

Reduced Risk of Non-Neovascular AMD in Cancer Patients Treated with Immune Checkpoint Inhibitors: A Propensity-Matched Cohort Study.

Lishinsky-Fischer et al.
Am J OphthalmolJan 7, 2026

This retrospective cohort study of 72,074 cancer patients found that immune checkpoint inhibitor therapy was associated with a 23% reduced risk of developing non-neovascular AMD over 5 years, with no effect on neovascular AMD risk.

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Choroidal Macrovessel Complicated by Choroidal Neovascularisation.

Albanese et al.
Am J OphthalmolJan 5, 2026

Insufficient information provided - only title and author information available without abstract content to summarize the clinical findings regarding choroidal macrovessel complicated by choroidal neovascularization.

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Immunopathology of the outer retina: crosstalk with the immune system.

Wildner et al.
Am J OphthalmolJan 4, 2026

RPE cells express FoxP3 transcription factor and upregulate inflammatory cytokines when stressed, suggesting they actively maintain immune privilege at the outer blood-retina barrier through mechanisms similar to regulatory T cells.

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Vascular Occlusions3 articles

CRVO, BRVO, retinal ischemia, macular edema from RVO

Retinal Arterial Emboli Visualized by Polarization-Sensitive OCT.

Terao et al.
OphthalmologyJan 5, 2026

Polarization-sensitive OCT successfully visualized retinal arterial emboli, providing enhanced detection and characterization capabilities compared to conventional imaging methods.

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Bilateral Retinal Artery Occlusion Associated with Aortic Atherosclerosis.

Funatsu et al.
OphthalmologyJan 5, 2026

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Stress Vasoreactivity Chorioretinopathy: A Bilateral, Reversible Choroidal Hypoperfusion After Systemic Trauma without Direct Ocular Injury.

Li et al.
Ocul Immunol InflammJan 4, 2026

Li et al. describe a novel condition termed Stress Vasoreactivity Chorioretinopathy (SVC) presenting as bilateral subretinal fluid following systemic trauma without direct ocular injury, which resolved rapidly with vasodilator therapy.

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Inherited Retinal Disease2 articles

IRDs, gene therapy, retinitis pigmentosa, LCA, Stargardt

Novel CNNM4 Variant Causing Jalili Syndrome in Identical Twin Sisters.

Shah et al.
Ophthalmol RetinaJan 9, 2026

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Vitreoretinal Abnormalities in Poretti-Boltshauser Syndrome: An Imaging Overview.

Gulkas et al.
Ophthalmol RetinaJan 7, 2026

Unable to provide a complete summary as only the title and author information were provided, without the full abstract content describing the study's findings on vitreoretinal abnormalities in Poretti-Boltshauser syndrome.

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Pediatric Retina2 articles

ROP, FEVR, Coats disease, retinoblastoma, pediatric vitreoretinal

Proteomic Profile in Retinopathy of Prematurity: A Secondary Analysis of the Mega Donna Mega Randomized Clinical Trial.

Lundgren et al.
JAMA OphthalmolJan 8, 2026

Early elevation of fibroblast growth factor 21 (FGF-21) and tissue plasminogen activator (tPA) in the first postnatal days strongly predicts severe ROP development in extremely preterm infants, suggesting metabolic stress as a key pathogenic mechanism.

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Aggressive-Retinopathy of Prematurity or Oxygen-Induced Retinopathy?

Singh et al.
Ophthalmol RetinaJan 7, 2026

Unable to provide summary as the abstract content was not included in the provided information.

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Posterior Uveitis1 article

Posterior uveitis, panuveitis, chorioretinitis, CMV retinitis, ocular inflammation

Sarcoid Uveitis Epidemiology, Systemic Treatment, and Complications: A Large United States National Database Study.

Shakarchi et al.
Ocul Immunol InflammJan 9, 2026

In this large US database study of over 108 million patients, 3.8% of sarcoidosis patients developed uveitis within 5 years, with one-third experiencing major ocular complications including cataract (35.7%), glaucoma (30.6%), and cystoid macular edema (16.1%).

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Ocular Oncology4 articles

Uveal melanoma, retinoblastoma, choroidal tumors, ocular metastases

Progressive Foveal Involvement in Congenital Hypertrophy of the Retinal Pigment Epithelium.

Carreira et al.
Ophthalmol RetinaJan 9, 2026

Unable to provide summary as the abstract content was not included in the provided information.

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Intraocular Solitary Fibrous Tumor.

Meng et al.
Ophthalmol RetinaJan 8, 2026

Unable to provide summary as the abstract content was not included in the provided information.

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Atypical Choroidal Melanocyte Depigmentation in Herpes Zoster Ophthalmicus.

Alegre-Ituarte et al.
OphthalmologyJan 7, 2026

The authors report an atypical case of choroidal melanocyte depigmentation occurring in association with herpes zoster ophthalmicus, representing an unusual ocular manifestation of this viral infection.

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Early Peripapillary and Macular Microvascular Changes Following Ruthenium-106 Plaque Brachytherapy For Uveal Melanomas.

Abdelkader et al.
Am J OphthalmolJan 4, 2026

OCTA detected early subclinical microvascular changes in 24 uveal melanoma patients following Ru-106 plaque brachytherapy, with radial peripapillary capillary density loss correlating with optic nerve radiation dose and visual decline.

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Complications & Safety1 article

Endophthalmitis, surgical complications, drug safety, adverse events

Retinal Vascular Rupture During Fluorescein Angiography.

Meng et al.
OphthalmologyJan 9, 2026

Unable to provide summary as the abstract content was not included in the submission, only the title and authors were provided.

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